Barna, M., Kucera, A., Hladikova, M., and Kucera, M. Randomized double-blind study: wound-healing effects of a Symphytum herb extract cream (Symphytumxuplandicum Nyman) in children. Jedlinszki N, Balzs B, Csnyi E, Csupor D. Penetration of lycopsamine from a comfrey ointment through human epidermis. Bleakley, C. M., McDonough, S. M., and MacAuley, D. C. Some conservative strategies are effective when added to controlled mobilisation with external support after acute ankle sprain: a systematic review. Comfrey ( Symphytum officinale) is an attractive ornamental plant used in gardening and medicine. View abstract. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. It is easily absorbed to leave your skin feeling fresh, soft and radiant. Please read the Topical Use Safety section of this article (above) before using. (2018). CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Copyright 1996-2023 Cerner Multum, Inc. The Food and Drug Administration (FDA) released an advisory in July 2001 recommending that comfrey products be removed from the market because of cases of hepatic veno-occlusive disease. Homeopathy. Lorem ipsum dolor sit nulla or narjusto laoreet onse ctetur adipisci. Avoid using comfrey extracts on broken skin or open wounds. J Pharmacopuncture 2021;24(4):196-205. Instructions. Ther Drug Monit 2001;23:698-708. Topically applied comfrey oil is associated with a wide range of health benefits and can help with certainissues including: Comfrey oil is good at helping with superficial cuts, scratches, and scrapes. root extraction help ease aching joints and muscles? If you choose to use comfrey, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Comfrey - please don't use it - The Herbal Horse and Pet We go to great efforts to ensure that the information on this page is accurate at the time that the page was last edited. Generic name: comfrey [COM-free] This includes androstenedione, bishop's weed, borage, chaparral, comfrey, DHEA, echinacea, garlic, germander, golden ragwort, hound's tongue, kava, licorice, niacin (vitamin B3), pennyroyal oil, red yeast, St. John's wort, and others. (2004). Molecules. The most common over-the-counter medication that can be toxic to the liver is acetaminophen (Tylenol). Available for Android and iOS devices. 2758955. Phytomedicine. This item: Terry Naturally Traumaplant Comfrey Cream - 1.76 oz (50 g) - Non-Staining Topical Botanical, Free of Toxic Pyrrolizidine Alkaloids (PAs) & Parabens - for External Use Only $20.76 ($11.80/Ounce) Dr. Christopher's Comfrey Ointment, 2 Ounce $11.99 ($6.00/Ounce) Dr Christopher's Formula Complete Tissue and Bone Ointment, 4 Ounce Book your free, one-to-one online consultation with one of our qualified advisors. cup organic sunflower oil Call your doctor for medical advice about . Comfrey is likley unsafe to take by mouth. 2012;20(11):1209-16. doi:10.1016/j.joca.2012.07.019, Zago LR, Prado K, Benedito VL, Pereira MM. Pabst H, Schaefer A, Staiger C, Junker-samek M, Predel HG. Save the remaining liquid alcohol portion. Rad. Comfrey oil shouldnt be used for cooking, like other types of cooking oil. Herbal drugs and phytopharmaceuticals. Join Rewards for Life today and we'll give you 300 points worth 3, Save 5% on your favourite products, plus get the lowest price from the last 90 days and free delivery on orders over 10. Its long, lance-shaped leaves can be up to 1 foot in length closer to the bottom of the stem and are shorter higher up the stem. 2758955. 2010;13(7-8):509-526. doi:10.1080/10937404.2010.509013, Staiger C. Comfrey: A clinical overview. View abstract. Supplements marketed for body-building (ex.. Registered in England: company no. Acupuncture for Chronic Pain: Update of an Individual Patient Data Meta-Analysis. The Herbal Academy makes neither medical claim, nor intends to diagnose or treat medical conditions. COMFREY Reviews and User Ratings: Effectiveness, Ease of Use - WebMD This site uses cookies to improve your experience. randomized double-blind study of 278 patients with fresh abrasions, a. topical preparation containing a 10% comfrey leaf extraction applied for 2-3 days reduced wound healing time of adults and children without side effects (Barna et al., 2012). While there can be a variety of causes for back pain, these small studies offer hopeful results that comfrey root may offer potential analgesic and anti-inflammatory benefits. . For one of these studies, the average time participants had experienced knee pain and stiffness leading up to the study was six and a half years! 2013;21(6):724-45. Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid. This was compared to 37.8% in the placebo group. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Dosage: How Much Comfrey Cream Should I Use? View abstract. View abstract. Herbal drugs and phytopharmaceuticals. Written by Cerner Multum. If you're considering using the cream, consult your healthcare provider first. After 2-4 weeks have passed, strain the root from the alcohol using a coffee filter inserted in a wire mesh strainer or similar setup. No comments. Pyrrolizidine alkaloids are very toxic to the liver and are also carcinogenic (cause cancer). Please read the Topical Use Safety section of this article (above) before using. Be sure to use comfrey root from a reputable source that has properly identified the species. They help us to understand how people use the website and give us the ability to provide targeted marketing to you. This makes quite a thick rich cream good for a body cream and an all healing cream . Maryland Heights, MO. Squish and squeeze as many leaves into as you can into the container. The leaves and stems of comfrey contain pyrrolizidine alkaloids that can cause toxic damage if ingested in excess (Ulbricht, 2010). Heard about essential oils but not quite sure about what they can do for you? Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. This is memorable if you have worked with it, and some use this quality to remember comfreys centuries-long useapplying comfrey over bones, bruises, sprains, and minor wounds with the intention to support mending! All rights reserved. Simply massage into the skin as required. You should never ingest comfrey by mouth. It contains chemicals that are poisonous. Chojkier M. Hepatic sinusoidal-obstruction syndrome: toxicity of pyrrolizidine alkaloids. Phytomedicine, 11(6), 470-477. https://doi.org/10.1016/j.phymed.2004.02.001, Kucera, A., Barna, M., Holcova, S., Horacek, O., Hladikov, M., & Ottillinger, B. Complement Ther Clin Pract. Comfrey cream may help treat knee osteoarthritis, according to a Cochrane review of topical herbal therapies. You can weight them down with a rock or brick. Liver injury from herbal and dietary supplements. Copyright Holland & Barrett Retail Limited, 2022. Shop buy 1 get 1 half price on all gut health products, Buy 1 get 1 Half Price | Plus an extra 20% off 25, App Exclusive | Get an extra 22% off 25 when you spend on the H&B App, Royal Mail strikes may cause a delay to our click and collect service, Looking for fitness advice & inspiration this New Year? Credit Solution Experts Incorporated offers quality business credit building services, which includes an easy step-by-step system designed for helping clients build their business credit effortlessly. Am J Med 1990;89:547-8. Br J Sports Med. Comfrey - The Lost Herbs Symphyti) in the treatment of ankle distorsions: Results of a multicenter, randomized, placebo-controlled, double-blind study. Follow all directions on the product label and package. My family has used comfy for ingrown toenails. cup organic, unrefined cocoa butter 2023 Dotdash Media, Inc. All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. , 43 volunteers with osteoarthritis used either a topical cream containing comfrey, tannic acid, and eucalyptus or a placebo cream 3x/ day for 6 weeks. Comfrey is traditionally used for the symptomatic treatment of minor sprains and bruises and is also known for its healing properties. Safety Alerts & Advisories: FDA Advises Dietary Supplement Manufacturers to Remove Comfrey Products From the Market. Complement Ther Med. Comfrey (Symphytum officinale) is a plant with yellow or purple flowers found in Europe, Asia, and North America. OTHER NAME(S): Ass Ear, Black Root, Blackwort, Bruisewort, Common. 2012;101(4):211-216. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Jurcu, R., & Jurcu, I. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Other prescription medicines that may harm the liver include: Some supplements may also harm the liver, including: It is essential to carefully read a supplement's ingredient list and nutrition facts panel to know which ingredients and how much of each ingredient is included. This is the tincture. Comfrey [Online article]. Symphyti) bei Sprunggelenks-distorsionen. View abstract. HOLLAND & BARRETT PRO VITAMIN E DAY CREAM 50ML This Vitamin E day cream works with your skin daily to hydrate and protect your skin. Frost R, O'meara S, Macpherson H. The external use of comfrey: a practitioner survey. Grube, B., Grunwald, J., Krug, L., and Staiger, C. Efficacy of a comfrey root (Symphyti offic. DOI:10.1211/PJ.2021.1.69803. Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials. Oral use of comfrey is not recommended because of potential liver damage. (10), 707-714. https://doi.org/10.1016/j.phymed.2005.06.001. The chemicals contained in comfrey may cause birth defects. 2013;163:5864 (2013) doi:10.1007/s10354-012-0162-4, Giannetti BM, Staiger C, Bulitta M, Predel HG. Cap, then label the jars with the date made and ingredients. Do not take comfrey without medical advice if you are using any of the following medications: This list is not complete. Regulatory Toxicology and Pharmacology, 83, 1-4. https://doi.org/10.1016/j.yrtph.2016.11.015. British Homeopathic Journal, 90(01), 21-28. https://doi.org/10.1054/homp.1999.0460. Please review this supplement label with your healthcare provider to discuss potential interactions with foods, other supplements, and medications. Need some help with an order or want to speak to a member of our Customer Services team? We currently have no information for COMFREY overview. Do not use this product without medical advice if you are pregnant. Potters Comfrey Oil | Holland & Barrett Shop our range of Potter's Herbals products at Holland & Barrett, including Potters Comfrey Oil. J Agric.Food Chem 2001;49(8):3942-3946. Comfrey is considered likely unsafe to use if you are nursing a baby. For topical comfrey cream, look for products labeled as free of pyrrolizidine alkaloids. Soaked foot in warm water with a few leaves of comfry. Efficacy and tolerance of a comfrey root extract (Extr. The Herbal Academy neither endorses them nor is in any way responsible for their content. One study in 120 patients with acute upper or lower back pain used either four grams (g) of comfrey root ointment or a placebo (sham treatment) three times daily for five days. We go to great efforts to ensure that the information on this page is accurate at the time that the page was last edited. Comfrey has been used in alternative medicine as a possibly effective aid in treating back pain, osteoarthritis, or tenderness and swelling caused by a sprain injury. Penetration of lycopsamine from a comfrey ointment through human epidermis. This soothing blend of herbal oils contains Comfrey (also known as Knitbone) and Eucalyptus Oil. Grube, B., Grnwald, J., Krug, L., & Staiger, C. (2007). Bhupesh started his career as a Clinical Toxicologist for Public Health England, advising healthcare professionals all around the country on how to manage clinical cases of adverse exposure to supplements, pharmaceuticals, cosmetics, industrial chemicals and agricultural products. Complementary Health Approaches for Chronic Pain: What the Science Says. Don't use comfrey products if you have or are at risk of having liver disease, cancer, or are taking any medication that affects the liver since it may increase the risk of liver toxicity. Tanret, I. and Duh, D. [Pharmaceutical sheet. Hepatology. Comfrey Cream Recipe for Achy Joints and Muscles - Herbal Academy Penetration of lycopsamine from a comfrey ointment through human epidermis. 98% Naturally derived. Potter's Herbals Comfrey Ointment for Minor Sprains and Bruises Those who used the comfrey ointment experienced improvements in pain, mobility, and quality of life. Capsicum Cream Holland And Barrett Recipes Comfrey root extracts have been used by herbalists and in folk traditions for centuries to soothe aches and pains. Electric bowl mixer (like a KitchenAid) or a blender Patients with hypersensitivity or allergic reactions to the plant should also avoid external use. Comfrey Uses, Benefits & Side Effects - Drugs.com Herbal Database When harvesting comfrey or buying from a non-commercial supplier, note that there is variety within the species. 6 Healing Benefits of Comfrey. 2012;(1):41-42. Stewart MJ, Steenkamp V. Pyrrolizidine poisoning: a neglected area in human toxicology. Stop using comfrey and call your healthcare provider at once if you have: liver problems--nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). 2 cups organic, unrefined coconut oil Using different formulations together increases the risk of an overdose. All Technology Jobs. Finally, well warn of any side effects associated with comfrey oil. CLICK HERE TO ENTER! J Hepatol 2003;39:437-46. 20 Rewards for Life points with this purchase, Potters Herbals Comfrey Ointment is a traditional herbal medicinal product used for the symptomatic relief of minor sprains and bruises, based on traditional use only. What are the benefits of using it? Megan Nunn, PharmD, is a community pharmacist in Tennessee with over twelve years of experience in medication counseling and immunization. It also came as a reference to the belief that comfrey can mend broken bones. In 2001, the Food and Drug Administration (FDA) banned oral comfrey products. She is passionate about providing evidence-based recommendations that make health decisions easier and improve lives. 2017;83:1-4. What Happens If I Use Too Much Comfrey Cream? Here's a look at research on comfrey cream for back pain, osteoarthritis, and ankle sprains. Although topical comfrey has been used for this indication, there's little evidence that it helps and can pose a big risk for nursing babies. It is called knitbone or boneset, referring to the bone-like growth of its roots. Supplement use should be individualized and vetted by a healthcare professional, such as a registered dietician, pharmacist, or healthcare provider. Therapeutic Research Faculty 2020. Nutrition C for FS and A. The study involved 43 patients with knee osteoarthritis and a six-week treatment period. Roeder E. Medicinal plants in Europe containing pyrrolizidine alkaloids. Scientific studies have shown comfrey oil can help reduce the likelihood leg ulcers will become infected.7, Topical application of comfrey oil has been shown to support the lower and upper back more than methyl nicotinate, the main ingredient in many muscle creams.8. Bagheri Z, Azizi A, Oshvandi K, Mohammadi Y, Larki-Harchegani A. Available at: https://www.cfsan.fda.gov/~dms/dspltr06.html. Find out how to use it here along with its benefits. Avoid comfrey with certain medical conditions, such as liver disease. Registered office: Samuel Ryder House, Barling Way, Nuneaton, Warwickshire CV10 7RH. Treatment with 4Jointz reduces knee pain over 12 weeks of treatment in patients with clinical knee osteoarthritis: a randomised controlled trial. Transfer the cooled oil and butter mixture to a standing electric mixer or blender. View abstract. Check regularly, but it should take about six weeks for all the leaves to break down into a thick, black liquid. Apply a small amount (not to exceed a teaspoon) topically 2-3x/day for up to 2 weeks. For External Use only Do not use if you are sensitive to any of the ingredients. After the consistency begins to thicken, turn the mixer up a little bit. This is not recommended due to the presence of chemicals that can cause organ damage and cancer. This recipe is contraindicated for small children and those with certain medical conditions. How to Make and Use Comfrey Fertilizer - The Spruce Osteoarthritis Cartilage. Choose organically grown comfrey when possible. Avoid with medications that induce CYP3A4 or are hepatotoxic (Natural Medicines, 2020). comfrey cream holland and barrett. In Western Europe, comfrey has been used topically for treating inflammatory disorders such as arthritis, gout, and thrombophlebitis, and internally for treating diarrhea. For this reason, some topical products are advertised as made from comfrey leaves, but it's safest to choose a PA-free product. A critical scoping review of external uses of comfrey (Symphytum spp.). Food and Drug Administration. Turn off heat and give it a good stir. Efficacy and tolerance of a comfrey root extract (Extr. Scoop the finished comfrey cream into sanitized glass jars. Glass bowl with a lid Avila C, Breakspear I, Hawrelak J, Salmond S, Evans S. A systematic review and quality assessment of case reports of adverse events for borage (Borago officinalis), coltsfoot (Tussilago farfara) and comfrey (Symphytum officinale). Other uses not proven with research have included skin wounds, skin ulcers, cough, sore throat, gum disease, joint pain, diarrhea, and other conditions. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. We cover all you need to know in this article. Two interesting studies found that a topical application of a product containing comfrey root extract helped with knee pain and stiffness. This is not a complete list of side effects and others may occur. Vickers AJ, Vertosick EA, Lewith G, et al. Rad. Efficacy of a comfrey root (Symphyti offic. Predel, H. G., Giannetti, B., Koll, R., Bulitta, M., & Staiger, C. (2005). Learn more in The Comfrey Controversy: Can and Should One Use Comfrey Internally? Barna, M., Kucera, A., Hladicova, M., and Kucera, M. [Wound healing effects of a Symphytum herb extract cream (Symphytum x uplandicum NYMAN: ): results of a randomized, controlled double-blind study].